Important safety information: Do not take large doses of vitamins while you use Nucleo Cmp Forte unless your doctor tells you to. It works by providing extra vitamins and minerals to the body when you do not get enough from your diet. The medication caused a modest improvement in patients with progressive spastic paraparesis and was free of side effects. Nucleo Cmp Forteis a vitamin and mineral supplement. Neurogenic bladder improved in 10 of 22 receiving the drug and 4 of 24 receiving placebo (NS) Somatosensitive evoked potentials improved in four of seven patients treated with the drug and in two of seven treated with placebo. Gait and spasticity improved in 7 of 22 patients receiving the drug and 1 of 24 receiving placebo (p < 0.05). Twenty two were treated with the drug and the rest with placebo. Gait, spasticity, degree of neurogenic bladder and somatosensitive evoked potentials were assessed during treatment.įorty six patients aged 25 to 79 years old were studied, 24 were female and 29 HTLV-1 positive. Usage of Nucleo CMP Forte in the combined treatment of patients has more expressed positive influence on problems with walking. Patients with the disease were randomly assigned to receive the Nucleus CMP forte (containing dysodic cytidinmonophosphate 5 mg, trisodic uridintriphosphate 3 mg and hydroxicobalamin 2 Mg) tid or placebo during six months. Nucleo Cmp Forte capsule contains Cytidineand Uridineas active ingredients. Nucleo Cmp Forte capsule may also be used for purposes not listed in this medication guide. To assess the effects of a medication containing cytidinmonophosphate, uridintriphosphate and vitamin B 12 in the treatment of progressive spastic. Nucleo Cmp Forte capsuleis used for Nucleoside reverse transcriptase inhibitors-related mitochondrial toxicity and other conditions. Idiopatic or HTLV-1 associated progressive spastic paraparesis does not have a clear etiology or treatment.
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